Radicular neuropathy is categorized in a group of rare disorders called hereditary sensory neuropathy. These are serious degenerative nerve system disorders which run in families and are caused by genetic mutations, and the neuropathy can progress to complete loss of feeling in the hands and feet, or to severe inflammation that eventually leads to ulcerations.
HSN-I
The radicular neuropathy called HSN-I causes complete sensory deficiencies to pain and temperature, typically leading to mutilating injuries and ulcerations in the fingers and toes, which then must eventually be amputated.
HSN-II
HSN-II radicular neuropathy symptoms begin with inflammation and loss of sensation in the fingers and toes, with ulcers forming. Lack of sensation tends to result in people neglecting the ulcers, leading to the need for amputation. This is a systemic disease beginning in early childhood.
HSN-III
HSN-III radicular neuropathy is present at birth, and also has the primary symptom of inability to feel pain and temperature in the extremities.
Additional HSN-III Symptoms
HSN-III has many additional symptoms, including constipation, diarrhea, vomiting, poor growth, repeated episodes of pneumonia, seizures and many others.
HSN-IV
HSN-IV radicular neuropathy causes muscle weakness and atrophy, mainly in the legs and occasionally in the hands.
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